Van de Ven Brace Ends Everton's Run at Brand New Stadium
Micky van de Ven became the first defender to score two goals in a Premier League game for Tottenham since Jan Vertonghen in spring 2013.
At a glance
Micky Van de Ven heads into the net twice in opening period
The home side's Jake O'Brien has goal ruled after video check
Pape Matar Sarr nets final goal in dying moments
The defeat is Everton's initial at their new ground
Micky van de Ven scored on two occasions as Tottenham prolonged their winning streak on the road in the Premier League and handed the Toffees their initial loss at their new home.
Everton were undefeated in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after more than a century at the conclusion of last season.
But Tottenham's leader Van de Ven pounced twice from set-pieces in the opening 45 minutes to place their impressive record at jeopardy, and they were failed to turn it around before Pape Matar Sarr - set up by ex-Everton forward Richarlison - headed home a third to seal the victory.
Jake O'Brien thought he had levelled the tally five minutes after Van de Ven's first goal, directing a powerful header past Guglielmo Vicario from an set-piece.
Beto, in the meantime, missed a handful of opportunities, while Vicario made a succession of excellent stops to guarantee the London club went five away games unbeaten in the Premier League.
But the video assistant referee intervened, instructing the match official to check the goal on the screen and the official decided that Jack Grealish and Iliman Ndiaye were in offside positions and had interfered with the Tottenham goalkeeper.
The win elevates the manager's side up to third in the division, a handful of points off local foes and table-toppers Arsenal.
The Merseyside club stay 14th and are six points ahead of the drop zone.
Tottenham analysis: The defender excels in role at both ends of pitch
After a drab midweek performance in the European competition against the French side, where they managed a only attempts on goal, Frank opted for Randal Kolo Muani up front instead of former Toffees player the Brazilian.
The summer signing was unable to influence the game before being replaced for the substitute after 60 minutes on the pitch, but it emerged he proved unnecessary in the end.
Defender Van de Ven converted into an offensive threat to be feared.
Tottenham's first goal came from a well-worked corner routine, with Rodrigo Bentancur heading the ball toward the six-yard box for an unmarked the defender to head home.
And Ven de Ven - filling in as captain in the Argentine's unavailability - notched his next goal in first-half stoppage time as he rose above Jordan Pickford to head home.
The Dutchman was just as impressive in defensive duties, combining well with Kevin Danso as the duo dealt superbly with the 34 crosses thrown their way by Everton.
Everton analysis: Toffees lacking striker's instinct
The club's recent stadium had been a happy hunting ground, but it appears the novelty may have faded slightly and fans headed to the gates after the midfielder's third for Tottenham.
The end in Everton's winning streak at home will not be a massive concern for David Moyes, but their attacking woes will be.
Beto and Thierno Barry - the Everton's pair of established strikers - had netted just one league goal between them before Sunday's match.
And they were failed to contribute to that poor tally on a damp and dreary evening on Merseyside.
Beto's performance was summed up when he opted to bicycle-kick a golden opportunity from close range, even with having room and time to readjust for a more conventional shot that would have tested the keeper.
The substitute, as well, was unable to influence the game after coming on for Beto in the 65th minute.
It wasn't for a shortage of chance. The majority of the home side's offensive moves came through Grealish and Ndiaye, who tirelessly whipped threatening balls into the Tottenham penalty area.
Upcoming fixtures for these two sides?
The Toffees: The team travel to the Stadium of Light in the top flight on Monday, 3 November at 20:00 GMT.
Spurs: Spurs go to St James' Park on Wednesday, 29 October for their fourth-round League Cup tie against the Magpies.